Best's vitelliform macular dystrophy, or Best’s Disease, is an autosomal dominant condition characterized by macular lesions that appear between the ages of 5 and 15 years. Most patients are visually asymptomatic or show only moderate visual loss until 40 to 50 years of age. In Best's disease, the ERG will be normal or nearly normal, however the EOG will be profoundly affected making it the preferred method for diagnosis.